Credit: The Green O

An adult-only hideaway beneath a sky as big as the ocean, near a roaring trout-brimming river, sewn amongst the pines, The Green O has only 12 accommodations. Poetically called ‘hauses,’ the design-forward suites encircle a freestanding restaurant, aptly known as Social Haus.

Credit: The Green O

Reward your inner child with Tree Haus, the woodland haven’s largest sanctum. It suspends 23 ft above ground, veritably part of the branches. Accessed by a spiral staircase, the 1,030-sq-ft refuge is resplendent with immense windows, features a luxurious bathroom with soaking tub, well-equipped kitchen and outdoor hot tub.

Credit: The Green O

Located within the same expanse of unspoiled terrain as parent retreat Paws Up, an upscale dude ranch, Green O keeps guests busy with an array of Western-intoned activities. $2,290 per night.

Credit: One&Only Mandarina

Knit beside a perfect beach along the rumbling Pacific Ocean on the lesser-traveled Riviera Nayarit, One&Only Mandarina nestles below a verdant mountain, brushed with a jungly rainforest. Eco-oriented, the resort gets accolades as a leader in sustainable luxury and low-density architectural design. Take over its Villa One, a paragon of en plein air liveability, certain to dissipate the stress.

Credit: One&Only Mandarina

With three bedrooms and a prodigious terrace, complete with pool, it spreads across two levels, each corner enhanced with Mexican design touches from handmade furniture to colorful art. A gym, private cinema and game room compete with the resort’s various offerings, easily reached from the villa. In residence, you’ll dine under the ministrations of a private chef and have your days deftly planned by the villa’s dedicated host. From $8,900 per night.

Credit: andBeyond Sossusvlei

Like the Namib Desert’s quiver trees or reedy plants sturdy enough to survive the world’s oldest desert’s harsh (but captivating) clime, eco-friendly andBeyond Sossusvlei Desert Lodge exudes a gravitas as profound as a whispered prayer. Architecturally composed of glass, stone and steel, it manages to shape-shift mystically into the scramble and swirls of sand.

Credit: andBeyond Sossusvlei

With just ten suites, it weaves itself into the gravely landscape, punctuated by dunes and rocky promontories. Blessed with an enchanted light by day and deeply dark skies at night, the location feels further away from urbanity than you’ve ever been. The two-bedroom Star Dune Suite tempts with its captivating vistas and split-level living areas.

Credit: andBeyond Sossusvlei

Unfold immense glass panels to unveil uninterrupted desert views or stand on the shaded verandah in awe. Swim laps in your personal pool, snuggle in front of the signature fireplace, choose a bottle from your walk-in wine cellar and linger in the glass-flanked rain shower to peer into its 180 degree panorama. From $4,772 per night.

Credit: Ales Photography

Located within the spellbinding Ashar Valley, Banyan Tree Alula practically disappears into the surrounding sand dunes and vast sandstone cliffs. Greatly lowering its impact on the environment, Banyan Tree Alula is formed from tented villas that dot the landscape, creating an oasis of serenity where travelers can tune out from the outside world.

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At Banyan Tree Alula, it’s the Dune Three-bedroom Pool Villa that’s truly special. The decor is decidedly contemporary blending modern minimalist stylings with handcrafted antiques adding authenticity to the humble abode.

Credit: Banyan Tree Alula

This 2,500-sq-ft villa features three impressively large bedrooms capable of sleeping six. It’s also fit for entertaining with a ten-person dinner table and private swimming pool.

Credit: Hillside Family Vancouver

Basking amid the unspoiled Unesco-designated Clayoquot Sound Biosphere Reserve, all-inclusive Clayoquot Wilderness Lodge fulfils that longing we’ve had since childhood to commune with the great outdoors — and be truly off grid. Both expert campers and novice en plein air buffs feel at home at this far flung outpost, poised on the edge of the Pacific Ocean on dramatic Vancouver Island.

Credit: Hillside Family Vancouver

Where mountain, forest and roiling sea collide, the clever nature camp hosts guests in sophisticated safari tents, ideal for resting between activities as diverse as canyoning, archery, horseback riding and hiking. For families or friends traveling together, The Hillside Family Tent shelters glampers in two conjoined tents, perched high on a hillside. En suite, the tents also boast heated floors, private outdoor cedar-sheathed showers and deep soaking tubs. From $5,800 per night.

Credit: Echo Base

For those unable to nab a seat on a billionaire’s rocket ship, opt for an earthly solution that’s arguably just as exotic. With a nod to space exploration, Echo conveys an out-of-this-world escape from the noise and buzz of our daily lives. An exclusive group’s dream buyout, the camp redefines remote. Installed at the base of the Henriksen Nunataks, mountain peaks that protrude from the ice, Echo Camp has six futuristic suites that stretch to around 17 ft in diameter.

Credit: Echo Base

Composed with mixed composite materials, with floor-to-ceiling windows so the external and internal fuse, the pods can be arranged as singles or doubles. Shared among guests, there’s a central shower unit, kitchen, dining and lounge area. The Platinum Pod, the largest and most commodious stay with a little lounge area, lies a bit further afield, promising eerily soothing quietude in the most quixotic of destinations. From $858,000 for exclusive use for 12 guests.

Credit: Tierra Patagonia

Three granite spires pinpoint the spot: southern Patagonia’s legendary Torres del Paine National Park, a miraculous sprawl of wildness — glaciers, rivers, mountains — enveloped amongst untamed Chilean hinterlands. Known for its spellbinding, transformational solitude, the region attracts intrepid travelers, athletes and philosophers.

Credit: Tierra Patagonia

Tierra Patagonia, pitched on the banks of Sarmiento Lake, architecturally mirrors the terrain. Designed by architect Cazu Zegers to summon thoughts of a colossal fossil unearthed, the extraordinary hotel has only 40 guest rooms, all sublime and roomy.

Credit: Tierra Patagonia

Most spacious, the Two-level Suite, kitted out with minimalist flair and rugged artfulness (think blankets knitted in natural fibers and crisp wood accents), delivers with a living area on top and a grand bedroom below. Floor-to-ceiling windows pay homage to the prodigious wilderness that surrounds you at every turn. From $2,750 per night.

Credit: Singita Private Villas

On a scale all its own, Singita knows how to meld luxury with edginess, euphoria with adrenaline bursts and unspoiled nature with pampering. Known for its lodges throughout Africa, it also offers nine private villas tucked away in the most illustrious bushlands and nature reserves.

Credit: Singita Private Villas

One of them, Ebony Villa, roosts on the banks of the Sand River in the midst of South Africa’s electric Big Cat Country. Two side-by-side family suites allow for both intimacy and connection for groups of up to eight fellow travelers.

Credit: Singita Private Villas

Accented with local art, handmade furniture and classical safari elements, Ebony Villa harmonizes with the landscape, while supplying creature comforts aplenty from four poster beds to a gleaming pool. Butlers (banakeli), chefs and safari guides customize your stay. From $20,105 per night.

Credit: One&Only Gorilla’s Nest

Partake in a soul-satisfying adventure trekking through Rwanda’s Volcanoes National Park in search of nomadic mountain gorillas, who roam free with their family groups in their natural habitat. You’ll spend hours treading through muck and bramble with park rangers at your side for the chance to sit with the massive primates for an hour of sheer bliss.

Credit: One&Only Gorilla’s Nest

Tired and muddy, you’ll happily return to your luxe hideaway: One&Only Gorilla’s Nest, situated on the verge of the park. Recall the joys of the day in the opulently appointed, treehouse-like Silverback Suite, designed to showcase views of volcanoes, farms and eucalyptus forests.

Credit: One&Only Gorilla’s Nest

Atmospheric with local art that reflects the colors of the landscape, the expansive sanctum flaunts a magnificent private bathroom, huge bedroom, a multi-level terrace (which offers views in every direction), oversized living and dining areas, and private pool. From $27,000 per night.

Credit: andBeyond Phinda Homestead

Chic, even quirky, the four suites and common areas that comprise the Phinda Homestead stand out for their contemporary design flourishes and au courant luxury. A bush home that playfully references 1980s elements in its furnishings, the villa looks out over some of South Africa’s most wildlife-rife, grassy woodlands. Situated on some 70 thousand acres of diverse reserve in KwaZulu-Natal near the Mkuze Game Reserve, the home easily accommodates families or groups.

Credit: andBeyond Phinda Homestead

Unlike many safari properties, Phinda Homestead accepts children of all ages, and features a nanny’s room for ease. Adorned with Zulu art and basketwork, the residence brandishes clever design motifs throughout, such as marble basins shaped like Zulu pots. Various common areas, a gym and massage room, library, kitchen, herb garden, and pool provide diversion between game drives led by the onsite dedicated guide and tracker. From $10,422.